THCV Weight Loss & Metabolism Study
Cannabinoid THCv..Everything You Want To Know About THCv
THCv represents a compelling step forward in the evolution of cannabinoid and terpene based nootropics. Its growing popularity reflects a shift toward natural, plant-derived support for appetite control, sustained energy and mental focus.
Golden Gardens Cannabinoid and Terpene formulas support achieving day to day self-directed goals tied to improved quality of life.
The 2025 THCV and CBD weight study
What researchers tested
In 2025, the peer-reviewed journal Cannabis published a placebo-controlled study on THCV and CBD. The study followed 44 adults, 31 women and 13 men, with an average age of about 52. Participants took one of two doses once a day for 90 days, using strips that dissolve against the inside of the mouth:
- Lower dose: 8mg THCV + 10mg CBD
- Higher dose: 16mg THCV + 20mg CBD
A third group took a placebo. Participants didn't change their diet or exercise routine during the study.
What they found
Both cannabinoid groups lost a statistically significant amount of weight compared with placebo, and the higher dose did better than the lower one. Researchers also recorded smaller waist measurements, along with improvements in blood pressure and cholesterol readings.
What it doesn't tell us
- It's small. The author noted that the high-dose and placebo groups had few participants.
- It tested oral strips only. It didn't test gummies, tinctures, vapes or flower, and results from one delivery method may not carry over to another.
- Industry-affiliated. The investigator was affiliated with the biotechnology company Nex Therapeutics, not a university.
- It's one study. Larger, independent trials are needed before anyone can draw firm conclusions.
THCV is not an approved weight-loss treatment. If you're managing your weight, a health condition or medications, talk with your doctor.
Study: Smith, G. L. "Weight Loss and Therapeutic Metabolic Effects of Tetrahydrocannabivarin (THCV)-Infused Mucoadhesive Strips." Cannabis, 2025.
NIH THCv STUDY THCV WEIGHT STUDY (CANNABIS, 2025)
THCv vs. THC: What's the Difference?
THC (tetrahydrocannabinol) is the main psychoactive compound in cannabis—it's what gives you that classic “high.” THCv while structurally similar, behaves very differently in our body.
- THCv has an entourage effect with CBD to feel more energizing than relaxing.
- Unlike THC, 20mg of THCv suppressed appetite rather than increase it.
- THCv acts more like a Sativa than a sedative Indica. Users often report increased mental clarity, alertness, and motivation.
THCv studies have shown promising results. Links below–
NIH THCv STUDY THCV WEIGHT STUDY (CANNABIS, 2025)
Where Does THCv Come From?
THCv is found in trace amounts in certain cannabis strains, particularly those originating from Africa or Southeast Asia.
Does THCv Get You High?
THCv isn't psychoactive until very high doses (200+ mg).
Is THCv Legal? Hemp derived THCv is legal
THCv stands out as a promising cannabinoid for those looking to enhance daily performance and balance through more intentional, functional use.